Cancer Chemoprevention by James A. Crowell Ph.D., Cathy J. Holmes Ph.D. (auth.),

By James A. Crowell Ph.D., Cathy J. Holmes Ph.D. (auth.), Raymond C. Bergan MD (eds.)

This quantity bargains a large review of subject matters on the topic of melanoma chemoprevention. It presents a evaluation of themes starting from simple learn arenas to medical trial layout, implementation, and interpretation. It covers all key parts worthwhile for figuring out the sphere of melanoma chemoprevention for the reader, for people wishing to go into this quarter of research, and for people looking information specifically parts of study, in terms of agent identity, easy technological know-how investigations and scientific trials. The genesis of this e-book relies at the indisputable fact that melanoma chemoprevention is a comparatively new and speedily evolving box spanning a wide range of disciplines, and forces researchers to deal with tough and intricate questions whose solutions aren't available.
Cancer Chemoprevention offers a prepared source whose value and purpose lie in its skill to collect and solidify disparate facts to explicitly define troublesome areas and to focus on destiny components of significant improvement. It offers vast outlines for present, ongoing and destiny instructions during this sector with numerous aim organ websites, written by means of specialists of their respective fields, whose fundamental examine focuses upon that particular box.

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Cancer Res. 11: 927-932, 1981. J. e. Influence oftotal dose and dose schedule on induction of urinary bladder cancer in the mouse by N-butyl-N-(4-hydroxybutyl)nitrosamine. Carcinogenesis 2: 251-254, 1981. , Paust, J. B. Influence of 15 retinoic acid amides on urinary bladder carcinogenesis in the mouse. Carcinogenesis 1: 1469-1472, 1982. L. e. Antipromotional activity of dietary N-( 4-hydroxyphenyl)retinamide in two-stage skin tumorigenesis in CD-I and SENCAR mice. Cancer Lett. 11: 133-138, 1986.

114. I 15. 116. 117. 118. 119. Agent Identification and Preclinical Testing Chemoprevention of MNU-induced mammary tumors in the mature rat by 4-HPR and tamoxifen. Anticancer Res. 12: 1147-1154, 1992. B. e. N-Butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder cancer in C57BLl6 x DBA/2 F I mice as a useful model for study of chemoprevention of cancer with retinoids. Cancer Res. 11: 927-932, 1981. J. e. Influence oftotal dose and dose schedule on induction of urinary bladder cancer in the mouse by N-butyl-N-(4-hydroxybutyl)nitrosamine.

Agent Identification and Preclinical Testing Marnett, LJ. Aspirin and the potential role of prostaglandins in colon cancer. Cancer Res. 52: 5575-5589, 1992. c. and Kelloff, GJ. Lipoxygenase inhibitors as potential cancer chemopreventives. Cancer Epidemiol. Biomarkers Prevo ~: 467--483, 1999. D. N. Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells. Cancer Res. 58: 362-366, 1998. , Dahiya, R. and Hughes-Fulford, M. Induction of cyclo-oxygenase-2 mRNA by prostaglandin E(2) in human prostatic carcinoma cells.

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