Animals with Novel Genes by Norman Maclean

By Norman Maclean

This booklet is ready transgenic animals--animals into which new genes were artificially brought. It has chapters through prime specialists at the current state-of-play in regards to the program of the transgenic expertise to various animal teams. Scientists have carried out experiments on an excellent variety of animal kinds, starting from protozoan cells, via nematode worms and fruit flies to many greater vertebrates, and this booklet offers an in-depth, updated, complete and authoritative account of the paintings with all such animal forms. The most probably effect of transgenic animals at the way forward for agriculture and medication is especially nice. those animals supply an unmatched experimental procedure for the examine of gene law, genetic points of disorder, and gene treatment. one of many ambitions of the booklet is accordingly to set transgenic animals within the context in their current and destiny contributions to technological know-how and medication.

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Rio, D. C. (1990). Molecular mechanisms regulating Drosophila P element transposition. Annu. Rev. Genet. 24, 543-78. Sippel, A. , Hecht, A. & Bonifer, C. (1992). The regulatory domain organization of eukanjotic genomes: Implications for stable gene transfer, in Transgenic Animals, ed. F. Grosveld & G. Kollias, pp. 1-26. London: Academic Press. Trends in Biotechnology. (1993). 11 (5), 156-215. Special volume devoted to gene therapy. Ulmer, J. B. et al. (1993). Heterologous protection against influenza by injection of DNA encoding a viral protein.

Grosveld & G. Kollias, pp. 211-46. London: Academic Press. Van Beusechem, V. W. & Valerio, D. (1992). Prospects for human gene therapy. In Transgenesis: Applications of Gene Transfer, ed. J. A. H. Murray, pp. 283-322. New York: Wiley. , Peters, B. & Constance, T. (1992). The epsilon globin gene silencer. J. Biol. Chem. 267, 111532-8. 2 Transgenic insects JULIAN M. 1 Introduction For many years, transgenic research in eukaryotic organisms has been dominated by only three species, namely Drosophila, the mouse and yeast.

We therefore feel it appropriate to devote the first half of this chapter to a description of the development of transgenic technology in Drosophila melanogaster and an overview of the ways in which this technology has been applied. The second section concentrates on attempts to apply the same technology to non-drosophilid insects. The future of transgenic insects is then briefly discussed in order to explore the potential that transgenic technology may have in insects of economic, agricultural and medical significance.

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